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Cancer Chemopreventive and Antimutagenic Potential of Certain Plants

Cancer Chemopreventive and Antimutagenic Potential of Certain Plants
21 %

1377  Kč 1 735 Kč

Sleva až 70% u třetiny knih
The present work deals with the toxicity, cancer chemopreventive, antioxidant and antimutagenic potential of alcoholic extracts of five plants namely, Aegle marmelos, Mentha piperita, Moringa oleifera, Pongamia pinnata and Sida acuta against uterine cervix carcinoma in Swiss albino mouse model. Acute toxicity testing was carried out as per OECD guidelines. Murphy's string method was followed for cervical tumor induction wherein 3-Methylcholantherene was used as the positive carcinogen. 90 days after the administration of the carcinogen, animals were examined for the development of pre cancerous and cancerous lesions. Antioxidant status of the animals was assessed by estimating the levels of hepatic antioxidant molecules viz., Superoxide dismutase, glutathione-S-Transferase and Reduced glutathione. For studying the antimutagenic effects of the test plants bone marrow chromosomal aberration assay and Micronucleus assay were employed.
Autor:
Nakladatel: LAP Lambert Academic Publishing
Rok vydání: 2011
Jazyk : Angličtina
Vazba: Paperback / softback
Počet stran: 184
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